Again from TRAINS Magazine:
[quote] Two cylinder locomotives always used 90-degree quartering; with this arrangement, the power pulses were more even than they would be with any other setting. They weren't perfect, but as good as could be gotten.
Most railroads had the right side crankpins leading the left. In other words, when the right rods were at their lowest point (the "bottom quarter") the left side was on front dead center. The Pennsylvania was the biggest user of left-hand lead locomotives. Someone theorized that it was because PRR had so much multiple-track territory; the most solid part of a multiple-track roadbed is toward the center, and since the side of a locomotive that has the lead is the side that pounds the track hardest, PRR wanted the locomotive to pound the most solid part of the roadbed - the left hand side.
Three-cylinder simple locomotives had the crankpins 120 degrees apart; the setting of the inside cylinder couldn't be seen, but the two outside cranks were 120 degrees apart and the inside one 120 degrees from each.
Baldwin built an experimental three-cylinder compound 4-10-2 in which the driving wheels were quartered with left-hand lead. The center cylinder was the high-pressure cylinder and its crank was 135 degrees from the outside cranks. This locomotive exists today at the Franklin Institute in Philadelphia.
There was never any effort made to synchronize the two engines of either a Mallet or a Simple Articulated or a Duplex-drive locomotive. In simple articulateds and duplexes it was thought beneficial in some quarters if the drivers of one engine were a fraction of an inch different from those of the other so the engines wouldn't get into synch.
Old Timer [quote]